Description

n-(Benzyloxycarbonyl)-L-Valine 1,2-Dibromoethyl Ester is a specialized, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block in peptide chemistry, offering a reactive handle for further functionalization while protecting the valine side chain. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the synthesis of complex peptides, peptidomimetics, and novel bioactive molecules. Its precise structure ensures high selectivity and yield in multi-step synthetic routes.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis for introducing L-valine residues with orthogonal protection.
• Pharmaceutical Research: Used in the development and scale-up of active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Bioconjugation: Serves as a precursor for creating linkers and probes in bioconjugation chemistry for drug delivery systems.
• Chemical Biology: Employed in the synthesis of enzyme inhibitors, receptor ligands, and other biologically active compounds for research.
• Process Chemistry: Utilized in optimizing synthetic routes for cost-effective and scalable production of peptide-based drugs.
• Academic Research: A valuable reagent for universities and research institutes studying peptide structure-activity relationships and new synthetic methodologies.

Basic Information

Product Name	n-(Benzyloxycarbonyl)-L-Valine 1,2-Dibromoethyl Ester
CAS No.	73680-51-0
Molecular Formula	C15H19Br2NO4
Molecular Weight	437.12 g/mol
Synonyms	Z-L-Valine 1,2-dibromoethyl ester; Cbz-L-Valine 1,2-dibromoethyl ester; N-Carbobenzoxy-L-valine 2,3-dibromoethyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanoic acid 2,3-dibromoethyl ester; L-Valine, N-[(phenylmethoxy)carbonyl]-, 2,3-dibromoethyl ester; Benzyl N-[(2S)-1-[(2,3-dibromoethoxy)carbonyl]-3-methylbutyl]carbamate; Z-Val-OCH2CHBr2
EINECS	Contact for details

Quality Control

Our n-(Benzyloxycarbonyl)-L-Valine 1,2-Dibromoethyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is sensitive to strong acids and organic solvents; ensure the container is compatible and stored separately from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.