Description

3-(2-Amino-1-Hydroxyethyl)Benzene-1,2-Diol is a specialized organic compound featuring a catechol core substituted with an aminoethanol side chain, making it a valuable chiral intermediate and building block. This structure is critical for the synthesis of complex molecules, particularly in the pharmaceutical sector where precise stereochemistry and functional group compatibility are paramount. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of adrenergic receptor agonists and antagonists, particularly for cardiovascular and respiratory medications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators that leverage its catechol moiety.
• Biochemical Research: Serves as a precursor or standard in enzymatic studies related to catecholamine biosynthesis and metabolism.
• Fine Chemical Production: Employed as a versatile building block for creating complex ligands, catalysts, and specialty polymers.
• Asymmetric Synthesis: Utilized in chiral pool synthesis and resolution processes to introduce stereogenic centers into target molecules.

Basic Information

Product Name	3-(2-Amino-1-Hydroxyethyl)Benzene-1,2-Diol
CAS No.	73660-93-2
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	1-(3,4-Dihydroxyphenyl)-2-aminoethanol; 3,4-Dihydroxy-β-aminoethylbenzene; Norphenylephrine; α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol; DL-Norphenylephrine; (±)-Norphenylephrine; 2-Amino-1-(3,4-dihydroxyphenyl)ethanol; β-Amino-3,4-dihydroxyhydrocinnamic alcohol
EINECS	Contact for details

Quality Control

Our production of 3-(2-Amino-1-Hydroxyethyl)Benzene-1,2-Diol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation (IR, NMR), chiral purity assessment, and quantification of key impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.