Description

3-Bromo-5-Chloropyridine is a versatile and high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for their synthetic processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Aromatic Substitution: The halogen atoms provide sites for substitution with various nucleophiles to create diverse pyridine libraries.

Basic Information

Product Name	3-Bromo-5-Chloropyridine
CAS No.	73583-39-8
Molecular Formula	C5H3BrClN
Molecular Weight	192.44 g/mol
Synonyms	5-Chloro-3-bromopyridine; 3-Bromo-5-chloropyridine; 5-Chloro-3-bromo-pyridine; Pyridine, 3-bromo-5-chloro-; 3-Br-5-Cl-Pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.