Description

Methyl (2S)-2-Amino-3-(4-Fluorophenyl)Propanoate CAS NO 73283-54-2 is a chiral, non-natural amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined, fluorinated phenylalanine backbone essential for constructing complex molecules with targeted biological activity. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), especially in therapeutic areas like neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated peptide analogs and protease inhibitors.
• API Development: Used in research and production of potential drug candidates targeting central nervous system (CNS) disorders.
• Peptidomimetics: Incorporation into peptide backbones to enhance metabolic stability and binding affinity.
• Asymmetric Synthesis: Serves as a starting material or resolving agent in stereoselective catalytic processes.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies and mechanism-based research.
• Agrochemical Synthesis: Potential intermediate for developing advanced, fluorinated active ingredients.

Basic Information

Product Name	Methyl (2S)-2-Amino-3-(4-Fluorophenyl)Propanoate
CAS No.	73283-54-2
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	(S)-Methyl 2-amino-3-(4-fluorophenyl)propanoate; L-4-Fluorophenylalanine methyl ester; Methyl L-4-fluorophenylalaninate; (S)-2-Amino-3-(4-fluorophenyl)propionic acid methyl ester; (2S)-2-Amino-3-(4-fluorophenyl)propanoic acid methyl ester; 4-Fluoro-L-phenylalanine methyl ester; F-Phe-OMe; Methyl (S)-2-amino-3-(p-fluorophenyl)propionate
EINECS	Contact for details

Quality Control

Our production of Methyl (2S)-2-Amino-3-(4-Fluorophenyl)Propanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for pharmaceutical applications. All materials are characterized by advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98.5%), enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.