Description

Dimethyl 4-(4-Methoxyphenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is a high-purity dihydropyridine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile synthetic intermediate and a potential pharmacophore in active pharmaceutical ingredient (API) development. It is primarily sought by research institutions and pharmaceutical manufacturers for the synthesis and optimization of novel therapeutic agents, particularly in the cardiovascular and neurological fields.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of calcium channel blockers and other dihydropyridine-based Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Chemical Synthesis: Serves as a precursor for more complex heterocyclic compounds and functionalized dihydropyridines.
• Academic & R&D: Employed in universities and contract research organizations (CROs) for exploratory chemistry and method development.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Dimethyl 4-(4-Methoxyphenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate
CAS No.	73257-47-3
Molecular Formula	C18H21NO5
Molecular Weight	331.37 g/mol
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(4-methoxyphenyl)-3,5-pyridinedicarboxylic acid dimethyl ester; Hantzsch Ester Derivative; Dimethyl 1,4-Dihydro-2,6-dimethyl-4-(p-methoxyphenyl)-3,5-pyridinedicarboxylate; 4-(4-Methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester; DHP Derivative; Dihydropyridine Ester; CAS 73257-47-3
EINECS	Contact for details

Quality Control

Our Dimethyl 4-(4-Methoxyphenyl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.