Description

(S)-(-)-Methyl 2-Chloropropionate is a high-purity chiral building block and intermediate essential for asymmetric synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, ensuring high enantiomeric purity in final products. This compound is critically needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing active ingredients, catalysts, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), including non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutics.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and fungicides where specific stereochemistry is required for biological activity.
• Catalyst and Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex flavors, fragrances, and other high-value specialty chemicals.
• Polymer Modification: Acts as a monomer or modifying agent for introducing chiral centers into specialty polymers and functional materials.
• Academic and R&D: A valuable reagent in research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-(-)-Methyl 2-Chopropionate
CAS No.	73246-45-4
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	(S)-Methyl 2-chloropropanoate; (S)-(-)-2-Chloropropionic Acid Methyl Ester; Methyl (S)-2-chloropropionate; (S)-Methyl α-chloropropionate; L-Methyl 2-chloropropionate; (-)-Methyl 2-chloropropionate; Methyl (2S)-2-chloropropanoate; (S)-2-Chloropropionic acid methyl ester
EINECS	Contact for details

Quality Control

Our (S)-(-)-Methyl 2-Chloropropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The product is moisture-sensitive; keep container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.