Description

3-(3-(2-Chloroethyl)-3-Nitrosourea)-3-Deoxyglucopyranose is a specialized nitrosourea derivative of a modified sugar molecule, representing a critical intermediate in advanced pharmaceutical research. This compound matters for its role in the development of targeted chemotherapeutic agents, particularly in the synthesis of novel prodrugs designed for selective activation. It is primarily needed by research institutions and pharmaceutical companies engaged in oncology drug discovery, medicinal chemistry, and the development of carbohydrate-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nitrosourea-based chemotherapeutic agents and prodrugs.
• Oncology Research: Used in preclinical studies to develop targeted cancer therapies that leverage sugar transporters for cellular uptake.
• Medicinal Chemistry: Serves as a crucial scaffold for structure-activity relationship (SAR) studies to optimize drug potency and reduce systemic toxicity.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) or other targeted delivery systems due to its reactive functional groups.
• Biochemical Research: Utilized as a tool compound to study DNA alkylation mechanisms and cellular resistance pathways associated with nitrosourea drugs.

Basic Information

Product Name	3-(3-(2-Chloroethyl)-3-Nitrosourea)-3-Deoxyglucopyranose
CAS No.	73237-82-8
Molecular Formula	C9H16ClN3O7
Molecular Weight	313.69 g/mol
Synonyms	3-Deoxy-3-[3-(2-chloroethyl)-3-nitrosoureido]-D-glucopyranose; 3-[[(2-Chloroethyl)nitrosoamino]carbonyl]amino-3-deoxy-D-glucopyranose; 3-Deoxy-3-[3-(2-chloroethyl)-3-nitrosoureido]-D-glucose; D-Glucose, 3-deoxy-3-[3-(2-chloroethyl)-3-nitrosoureido]-; Chlorozotocin analog; CCNU-Glucose derivative
EINECS	Contact for details

Quality Control

Our 3-(3-(2-Chloroethyl)-3-Nitrosourea)-3-Deoxyglucopyranose is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and thermal degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.