Description

2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylic Acid is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is prized for its unique molecular architecture, which combines an imidazopyridine core with a carboxylic acid handle and a metabolically stable trifluoromethyl group. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its specific structure makes it a critical intermediate for developing compounds with enhanced biological activity and improved physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting the central nervous system (CNS), inflammation, and infectious diseases.
• Agrochemical Research: Serves as a building block for designing new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Precursor: Used in the synthesis of advanced organic materials, including ligands for catalysis and components for organic electronic devices.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Product Name	2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylic Acid
CAS No.	73221-19-9
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	2-(Trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid; Imidazo[1,2-a]pyridine-3-carboxylic acid, 2-(trifluoromethyl)-; 2-Trifluoromethylimidazo[1,2-a]pyridine-3-carboxylic Acid; 73221-19-9; 2-(Trifluoromethyl)-3-imidazo[1,2-a]pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results for identity, purity (HPLC), and impurity profile, is supplied with each shipment to guarantee traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.