Description

n-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate is a key protected derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound serves as a vital advanced synthetic intermediate for the production of complex glycoconjugates, sialosides, and glycomimetics. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel antiviral agents, cancer therapeutics, and diagnostic tools that target cell-surface glycans.

Application

• Glycoconjugate Synthesis: A crucial building block for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycoproteins, and glycolipids.
• Pharmaceutical Intermediates: Used in the research and production of sialidase inhibitors, anti-influenza drugs, and other therapeutics targeting sialic acid-mediated biological pathways.
• Biochemical Research: Serves as a standard and precursor in studies of cell recognition, immune response, and bacterial/viral pathogenesis involving sialic acid receptors.
• Diagnostic Development: Employed in the manufacture of diagnostic reagents and probes for detecting pathogens or cellular changes associated with sialic acid expression.
• Glycomimetics & Drug Discovery: A key starting material for designing and synthesizing stable glycomimetic compounds with potential therapeutic applications.

Basic Information

Product Name	n-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate
CAS No.	73208-82-9
Molecular Formula	C22H31NO15
Molecular Weight	549.48 g/mol
Synonyms	Methyl 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosidonic acid 2,4,7,8,9-pentaacetate; Methyl N-acetyl-α-neuraminate pentaacetate; Sialic Acid Methyl Ester Pentaacetate; Neu5Ac Methyl Ester Pentaacetate; NANA Methyl Ester Pentaacetate; 5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid methyl ester pentaacetate; Methyl (methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosid)onate
EINECS	Contact for details

Quality Control

Our n-Acetylneuraminic Acid Methyl Ester Pentaacetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccant after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.