Description

n-Acetyl-2-o-Methyl-A-Neuraminic Acid Methyl Ester 4,7,8,9-Tetraacetate is a key protected derivative of sialic acid, a crucial carbohydrate moiety in glycobiology. This compound matters as a vital synthetic intermediate and building block for the preparation of more complex sialosides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, antiviral drug discovery, and the development of diagnostic reagents and vaccines.

Application

• Glycoconjugate Synthesis: A critical protected intermediate for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycoproteins, and glycolipids.
• Antiviral Research: Used in the development of sialidase inhibitors and other antiviral agents that target viral entry mechanisms involving sialic acid receptors.
• Biochemical Tool: Serves as a substrate or inhibitor in enzymatic studies of sialidases (neuraminidases) and sialyltransferases.
• Vaccine Adjuvant Development: Investigated for its potential role in modulating immune responses as part of synthetic antigen constructs.
• Diagnostic Reagent Production: Employed in the manufacture of reagents for detecting and characterizing sialic acid-binding proteins (lectins) and antibodies.
• Medicinal Chemistry: A versatile starting material for creating novel drug candidates targeting inflammation, cancer metastasis, and bacterial infections.

Basic Information

Product Name	n-Acetyl-2-o-Methyl-A-Neuraminic Acid Methyl Ester 4,7,8,9-Tetraacetate
CAS No.	73208-80-7
Molecular Formula	C22H33NO13
Molecular Weight	519.50 g/mol
Synonyms	Methyl 5-acetamido-2,4,7,8,9-penta-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonate; Methyl (methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosid)onate; 2-O-Methyl-Neu5Ac Methyl Ester Tetraacetate; Sialic Acid Methyl Ester Tetraacetate Derivative; Neu5Ac2Me Methyl Ester Tetraacetate; Peracetylated Methyl Sialate; Ac4Neu5Ac2Me Methyl Ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-2-o-Methyl-A-Neuraminic Acid Methyl Ester 4,7,8,9-Tetraacetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.