Description

2-(Tetrahydro-Pyran-2-Yloxy)-Propionic Acid Ethyl Ester is a versatile chiral building block and protected hydroxy acid derivative, essential for the synthesis of complex organic molecules. Its primary value lies in its role as a key intermediate in pharmaceutical and fine chemical manufacturing, where it provides a protected functional handle for stereoselective synthesis. This compound is particularly needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the production of active pharmaceutical ingredients (APIs), especially in the synthesis of β-amino acids, peptides, and other bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or auxiliary in stereoselective reactions to construct molecules with defined three-dimensional architecture.
• Fine Chemical Production: Serves as a protected glycolic acid derivative for the manufacture of specialty chemicals, flavors, and fragrances.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators that require specific chiral centers for activity.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer for creating specialized polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies.

Basic Information

Item	Detail
Product Name	2-(Tetrahydro-Pyran-2-Yloxy)-Propionic Acid Ethyl Ester
CAS No.	73208-70-5
Molecular Formula	C10H18O4
Molecular Weight	202.25 g/mol
Synonyms	Ethyl 2-((Tetrahydro-2H-pyran-2-yl)oxy)propanoate; Ethyl 2-(Tetrahydro-2H-pyran-2-yloxy)propionate; 2-(THP-Oxy)propionic Acid Ethyl Ester; O-THP-protected Ethyl Lactate; Ethyl 2-[(Oxan-2-yl)oxy]propanoate; 2-(Tetrahydropyran-2-yloxy)propionic acid ethyl ester; Ethyl α-[(tetrahydro-2H-pyran-2-yl)oxy]propionate
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-Pyran-2-Yloxy)-Propionic Acid Ethyl Ester is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We can support development projects requiring compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.