Description

Pyrrolo(1,2,3-Ef)(1,5)Benzodiazepin-6(7H)-One, 1,2,3,4-Tetrahydro-9-Chloro- is a high-purity, specialized benzodiazepine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological intermediate for synthesizing novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates and active pharmaceutical ingredients (APIs).

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel benzodiazepine-based therapeutics.
• Neurological & Psychiatric Drug Research: Used in R&D for potential anxiolytic, sedative, and anticonvulsant drug candidates.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to optimize pharmacological profiles.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for new chemical entities (NCEs).
• Academic & Institutional Research: Supports fundamental research in neuropharmacology and organic chemistry at universities and research institutes.

Basic Information

Item	Details
Product Name	Pyrrolo(1,2,3-Ef)(1,5)Benzodiazepin-6(7H)-One, 1,2,3,4-Tetrahydro-9-Chloro-
CAS No.	73200-68-7
Molecular Formula	C13H11ClN2O
Molecular Weight	246.69 g/mol
Synonyms	9-Chloro-1,2,3,4-tetrahydropyrrolo[1,2,3-ef][1,5]benzodiazepin-6(7H)-one; 9-Chloro-1,2,3,4-tetrahydro-6H-pyrrolo[1,2,3-ef][1,5]benzodiazepin-6-one; 9-Chloro-THPBD; Pyrrolobenzodiazepine Chloro Derivative; 73200-68-7; 9-Cl-THPBD; 9-Chloro-tetrahydropyrrolobenzodiazepinone
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade Pyrrolo(1,2,3-Ef)(1,5)Benzodiazepin-6(7H)-One, 1,2,3,4-Tetrahydro-9-Chloro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.