Description

4-Nitrophenoxycarbonyl Methyl Disulfide is a specialized organic compound featuring a disulfide linkage and a reactive 4-nitrophenoxycarbonyl group. This unique structure makes it a valuable intermediate for synthesizing thiol-reactive probes, cross-linking agents, and functionalized polymers. It is primarily sought by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for applications requiring controlled chemical modification of sulfhydryl groups.

Application

• Bioconjugation Reagent: Used for the site-specific labeling and cross-linking of peptides, proteins, and antibodies via cysteine residues.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of drug candidates, particularly those targeting thiol-dependent biological pathways.
• Polymer Modification: Enables the functionalization of polymers and surfaces to introduce disulfide bonds or reactive handles for further chemistry.
• Proteomics Research: Employed in the development of activity-based probes and affinity tags for studying enzyme activity and protein interactions.
• Chemical Biology Tool: Facilitates the study of redox biology and thiol-disulfide exchange processes in cellular systems.
• Cross-linking Agent: Used to create reversible or cleavable linkages in material science and biomaterial fabrication.

Basic Information

Product Name	4-Nitrophenoxycarbonyl Methyl Disulfide
CAS No.	73143-98-3
Molecular Formula	C9H7NO5S2
Molecular Weight	273.29 g/mol
Synonyms	4-Nitrophenyl Methyl Disulfide Carbonate; Bis(4-nitrophenyl) Disulfide Carbonate Derivative; Methyl Disulfide 4-Nitrophenyl Carbonate; p-Nitrophenoxycarbonyl Methyl Disulfide; S-(4-Nitrophenoxycarbonyl) Methyl Disulfide; 4-Nitrophenyl S-Methyl Dithiocarbonate; (4-Nitrophenoxy)carbonyl Methyl Disulfide
EINECS	Contact for details

Quality Control

Our 4-Nitrophenoxycarbonyl Methyl Disulfide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.