Description

1-Azidonaphthalene-5-Sulfonate is a specialized aromatic sulfonate derivative functionalized with a reactive azido group, making it a valuable intermediate for advanced synthesis. This compound is particularly significant for its role in click chemistry and photoaffinity labeling applications, enabling the efficient construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel bioactive compounds, polymers, and probes.

Application

• Click Chemistry Reagent: Serves as a key building block in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer synthesis.
• Photoaffinity Labeling (PAL): Used to study protein-ligand interactions and identify binding sites due to the photolabile azido group that generates reactive nitrenes upon UV irradiation.
• Pharmaceutical Intermediate: Employed in the research and development of new drug candidates, particularly for creating targeted conjugates and prodrugs.
• Polymer & Materials Science: Facilitates the surface functionalization of nanomaterials and the synthesis of cross-linked polymers with tailored properties.
• Biochemical Probes: Utilized in the design of fluorescent or affinity tags for imaging and detecting biological targets.
• Agrochemical Research: Acts as an intermediate in synthesizing novel active ingredients with specific modes of action.

Basic Information

Item	Details
Product Name	1-Azidonaphthalene-5-Sulfonate
CAS No.	73105-93-8
Molecular Formula	C10H6N3NaO3S (Sodium salt)
Molecular Weight	279.23 g/mol
Synonyms	1-Azidonaphthalene-5-sulfonic acid sodium salt; Sodium 1-azidonaphthalene-5-sulfonate; 5-Azido-1-naphthalenesulfonate; Azidonaphthalene sulfonate; Naphthalene-1-azido-5-sulfonate; Photoaffinity labeling reagent; Click chemistry azide; PAL reagent
EINECS	Contact for details

Quality Control

Our 1-Azidonaphthalene-5-Sulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.