Description

Neptamustine CAS NO 73105-03-0 is a specialized alkylating agent belonging to the nitrosourea class of compounds. This compound is of significant interest in pharmaceutical research and development due to its potential as a chemotherapeutic agent. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel oncology treatments.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of potential anticancer drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of alkylation and DNA cross-linking.
• Reference Standard: Employed as a high-purity analytical standard in method development and quality control for related pharmaceutical products.
• Preclinical Development: Utilized in the formulation and testing of experimental chemotherapeutic agents in laboratory settings.
• Academic Research: Applied in university and institutional labs for studying the structure-activity relationships of nitrosourea compounds.

Basic Information

Product Name	Neptamustine
CAS No.	73105-03-0
Molecular Formula	C9H16ClN3O3
Molecular Weight	249.70 g/mol
Synonyms	1-(2-Chloroethyl)-3-(2-hydroxyethyl)-3-(3-methylbutyl)-1-nitrosourea; 1-(2-Chloroethyl)-3-(2-hydroxyethyl)-3-(3-methylbutyl)nitrosourea; NSC-344035; Neptamustin; NCI 60 Screened Compound
EINECS	Contact for details

Quality Control

Our Neptamustine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. The material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.