Description

N,N'-Hexamethylenebis(3-Pyridinecarboxamide) is a specialized organic compound featuring a hexamethylene bridge connecting two nicotinamide moieties. This structure makes it a valuable building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring rigid, amide-linked bis-heterocyclic scaffolds.
• Ligand Synthesis: Used in the preparation of chelating ligands for metal catalysis and coordination chemistry due to the presence of multiple nitrogen donor atoms.
• Polymer Modification: Acts as a chain extender or cross-linking agent in the production of specialty polyamides and polyurethanes to enhance material properties.
• Agrochemical Research: Employed as a synthetic intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Bioconjugation Chemistry: Useful in designing linkers for bioconjugates and prodrugs, leveraging its amide bonds and spacer length.

Basic Information

Product Name	N,N'-Hexamethylenebis(3-Pyridinecarboxamide)
CAS No.	73041-73-3
Molecular Formula	C20H24N4O2
Molecular Weight	352.44 g/mol
Synonyms	1,6-Hexanediylbis[3-pyridinecarboxamide]; N,N'-Hexane-1,6-diylbis(nicotinamide); Bis(3-pyridylcarbamoyl)hexane; Nicotinamide, N,N'-hexamethylenebis-; 1,6-Bis(nicotinamido)hexane; Hexamethylenebisnicotinamide; N1,N6-Bis(pyridine-3-carbonyl)hexane-1,6-diamine
EINECS	Contact for details

Quality Control

Our N,N'-Hexamethylenebis(3-Pyridinecarboxamide) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.