Description

4-Chloro-6-Hydroxypyridine-3-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular construction. Industries such as pharmaceutical R&D, agrochemical manufacturing, and fine chemical production need this high-purity intermediate to drive innovation in their product pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides and pesticides, where its pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in homogeneous catalysis and metal complexation.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value molecules for research and specialty material applications.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	4-Chloro-6-Hydroxypyridine-3-Carboxylic Acid
CAS No.	73038-85-4
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	3-Carboxy-4-chloro-6-hydroxypyridine; 4-Chloro-6-hydroxy-3-pyridinecarboxylic acid; 6-Hydroxy-4-chloronicotinic acid; 4-Chloro-6-hydroxynicotinic acid; 4-Chloro-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 4-Chloro-6-pyridone-3-carboxylic acid; 73038-85-4; 4-Chloro-6-hydroxypyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Hydroxypyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.