Description

1,3-Di-o-Acetyl-2-(Acetylamino)-2-Deoxy-4,6-o-Isopropylidene-D-Glucopyranose, also known as 1,3-Di-o-Acetyl-4,6-o-Isopropylidene-GlcNAc, is a key protected derivative of N-acetylglucosamine, serving as a critical chiral building block and synthetic intermediate. This compound is valued for its role in facilitating stereoselective glycosylation reactions and protecting group strategies in complex carbohydrate synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors who require high-purity intermediates for developing active pharmaceutical ingredients (APIs), glycoconjugates, and novel biomaterials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex glycosylated molecules, including antiviral agents, antibiotics, and other therapeutic compounds.
• Glycobiology Research: Used as a protected monosaccharide building block for the chemical and enzymatic synthesis of oligosaccharides, glycopeptides, and glycolipids.
• Carbohydrate Chemistry: Serves as a versatile intermediate for introducing the GlcNAc moiety in a controlled manner, enabling studies on glycosylation mechanisms and carbohydrate-protein interactions.
• Bioconjugate Development: Employed in the creation of labeled glycans, vaccine components, and targeted drug delivery systems that utilize carbohydrate motifs.
• Process Chemistry: Used in scale-up synthesis for the production of glycosidase inhibitors and other sugar-based pharmaceuticals.
• Standards and Reference Materials: Provides a high-purity standard for analytical method development and quality control in carbohydrate analysis.

Basic Information

Product Name	1,3-Di-o-Acetyl-2-(Acetylamino)-2-Deoxy-4,6-o-Isopropylidene-D-Glucopyranose
CAS No.	73024-78-9
Molecular Formula	C15H23NO8
Molecular Weight	345.35 g/mol
Synonyms	1,3-Di-O-acetyl-4,6-O-isopropylidene-N-acetylglucosamine; 1,3-Di-O-acetyl-2-acetamido-2-deoxy-4,6-O-isopropylidene-D-glucopyranose; 4,6-O-Isopropylidene-N-acetylglucosamine 1,3-diacetate; 2-Acetamido-1,3-di-O-acetyl-2-deoxy-4,6-O-isopropylidene-D-glucopyranose; GlcNAc(1,3-Ac2-4,6-iPr2); Protected N-Acetylglucosamine Derivative; 73024-78-9
EINECS	Contact for details

Quality Control

Our 1,3-Di-o-Acetyl-4,6-o-Isopropylidene-GlcNAc is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity suitable for research and synthesis. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.