Description

3-Bromo-2,4-Diaminopyridine is a versatile halogenated diaminopyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and amine functional groups, makes it a valuable intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A high-purity intermediate supplied for custom synthesis projects and scale-up processes under cGMP guidelines.

Basic Information

Product Name	3-Bromo-2,4-Diaminopyridine
CAS No.	72921-94-9
Molecular Formula	C5H7BrN3
Molecular Weight	189.03 g/mol
Synonyms	2,4-Diamino-3-bromopyridine; 3-Bromo-2,4-pyridinediamine; 3-Bromopyridine-2,4-diamine; 3-Bromo-2,4-diaminopyridine; 72921-94-9; 3-Br-2,4-DAPy
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4-Diaminopyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality standards align with ICH guidelines, and we can support development projects requiring material manufactured under current Good Manufacturing Practice (cGMP) conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.