Description

6-(4-Fluorophenyl)-2,3-Dihydro-5-(4-Pyridinyl)Imidazo[2,1-B]Thiazole Dihydrochloride is a high-purity, non-racemic organic salt with significant potential as a key intermediate in advanced pharmaceutical research and development. Its complex heterocyclic structure, featuring fused imidazothiazole, fluorophenyl, and pyridinyl moieties, makes it a valuable building block for medicinal chemistry, particularly in the synthesis of novel bioactive molecules. This compound is primarily targeted at research institutions, pharmaceutical companies, and CROs (Contract Research Organizations) engaged in drug discovery programs for central nervous system (CNS) disorders, oncology, and anti-infective agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: May be utilized in vitro to study enzyme inhibition, receptor binding, or other pharmacological mechanisms.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Used in university and institutional labs for synthetic organic chemistry projects and the development of new heterocyclic compounds.

Basic Information

Product Name	6-(4-Fluorophenyl)-2,3-Dihydro-5-(4-Pyridinyl)Imidazo[2,1-B]Thiazole Dihydrochloride
CAS No.	72873-74-6
Molecular Formula	C16H13FN4S · 2HCl
Molecular Weight	401.29 g/mol (Free base: 312.37 g/mol)
Synonyms	6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride; 6-(4-Fluorophenyl)-5-(4-pyridinyl)-2,3-dihydroimidazo[2,1-b]thiazole dihydrochloride; Imidazo[2,1-b]thiazole, 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-, dihydrochloride; 72873-74-6; 6-(p-Fluorophenyl)-2,3-dihydro-5-(4-pyridyl)imidazo[2,1-b]thiazole dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)-2,3-Dihydro-5-(4-Pyridinyl)Imidazo[2,1-B]Thiazole Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.