Description

2-Bromo-1,6-Naphthyridine is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactivity as an intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and researchers in the life sciences sector who require high-purity intermediates for drug discovery, material science, and the development of functional chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the naphthyridine scaffold's bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Biology: Utilized as a molecular probe or tag in bioconjugation and target identification studies.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry and process chemistry optimization.

Basic Information

Product Name	2-Bromo-1,6-Naphthyridine
CAS No.	72754-06-4
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	1,6-Naphthyridine, 2-bromo-; 2-Bromo-1,6-naphthyridine; 2-Bromonaphthyridine; 72754-06-4; 2-Bromo[1,6]naphthyridine; 2-Bromo-1,6-diazanaphthalene; Bromo-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,6-Naphthyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous demands of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.