Description

Ethyl 3-Oxopiperidine-4-Carboxylate Hydrochloride is a high-purity pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its role as a key precursor for the development of complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in the synthesis of novel piperidine-based compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the piperidine scaffold.
• Medicinal Chemistry Research: Used in the discovery and development of new therapeutic agents, including potential treatments for neurological disorders and other diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides that require complex heterocyclic structures.
• Fine Chemical Production: Employed in custom synthesis and the production of specialty chemicals for various high-value industrial applications.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in laboratories.

Basic Information

Product Name	Ethyl 3-Oxopiperidine-4-Carboxylate Hydrochloride
CAS No.	72738-09-1
Molecular Formula	C8H13NO3 · HCl
Molecular Weight	207.65 g/mol (Free base: 171.19 g/mol)
Synonyms	Ethyl 4-piperidone-3-carboxylate hydrochloride; Ethyl 3-oxo-4-piperidinecarboxylate hydrochloride; 4-Carbethoxy-3-piperidone hydrochloride; 3-Oxo-4-piperidinecarboxylic acid ethyl ester hydrochloride; 4-(Ethoxycarbonyl)-3-piperidinone hydrochloride; Ethyl 4-oxo-3-piperidinecarboxylate hydrochloride (tautomer); 72738-09-1; 4-Piperidinecarboxylic acid, 3-oxo-, ethyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 3-Oxopiperidine-4-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.