Description

4-Hydroxymethyl-Nicotinic Acid is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a hydroxymethyl group and a carboxylic acid on the nicotinic acid scaffold, makes it a valuable intermediate for creating complex molecules with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients and fine chemicals. Its reliable quality and consistent performance are paramount for ensuring the success of downstream manufacturing processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals.
• Bioconjugation and Linker Chemistry: The reactive functional groups enable its use in creating bioconjugates for diagnostic and therapeutic applications.
• Academic and Industrial R&D: Serves as a standard reagent in research laboratories for method development and exploratory chemistry.

Basic Information

Product Name	4-Hydroxymethyl-Nicotinic Acid
CAS No.	72726-63-7
Molecular Formula	C7H7NO3
Molecular Weight	153.14 g/mol
Synonyms	4-(Hydroxymethyl)nicotinic acid; 4-(Hydroxymethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-(hydroxymethyl)-; Nicotinic acid, 4-hydroxymethyl-; 4-Carboxy-3-pyridinemethanol; 4-Pyridinemethanol-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Hydroxymethyl-Nicotinic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via modern techniques like HPLC and NMR. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards. We support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.