Description

(E)-2-Methyl-2-Butenoic Acid [(3Ar,4R,6E,8S,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-8-Hydroxy-6,10-Dimethyl-3-Methylene-2-Oxocyclodeca[B]Furan-4-Yl] Ester is a complex, high-purity chemical ester with a defined stereochemistry, making it a valuable advanced intermediate for specialized synthesis. Its intricate fused-ring structure is critical for research and development in creating novel compounds with specific biological or material properties. This product is essential for pharmaceutical R&D chemists and fine chemical manufacturers working on complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in steroid-like or complex macrocyclic compound research.
• Advanced Organic Synthesis: Used in academic and industrial R&D for constructing complex, polycyclic molecular frameworks with specific stereocenters.
• Medicinal Chemistry Research: Serves as a precursor for developing new chemical entities (NCEs) with potential therapeutic applications.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for research and niche industrial applications.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in related compound analysis.

Basic Information

Product Name	(E)-2-Methyl-2-Butenoic Acid [(3Ar,4R,6E,8S,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-8-Hydroxy-6,10-Dimethyl-3-Methylene-2-Oxocyclodeca[B]Furan-4-Yl] Ester
CAS No.	72704-04-2
Molecular Formula	C20H28O5
Molecular Weight	348.44 g/mol
Synonyms	2-Methyl-2-butenoic acid (3aR,4R,6E,8S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-8-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester; Tiglic acid ester of a sesquiterpene lactone derivative; (E)-2-Methylbut-2-enoic acid [(3aR,4R,6E,8S,10E,11aR)-octahydro-8-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl] ester; CAS 72704-04-2; A complex sesquiterpenoid ester; 2-Butenoic acid, 2-methyl-, (3aR,4R,6E,8S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-8-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (E)-
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-2-Butenoic Acid Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.