Description

1,6-Naphthyridine-3-Carboxylic Acid, 1,2-Dihydro-4-Hydroxy-2-Oxo-, Ethyl Ester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold for the synthesis of potential drug candidates, including kinase inhibitors and antimicrobial agents.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile naphthyridine core.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Fine Chemical Synthesis: Acts as a building block for creating complex molecules used in material science and specialty chemicals.
• Academic Research: Utilized in universities and research institutes for exploring new heterocyclic chemistry and reaction methodologies.
• Contract Research and Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Product Name	1,6-Naphthyridine-3-Carboxylic Acid, 1,2-Dihydro-4-Hydroxy-2-Oxo-, Ethyl Ester
CAS No.	72668-49-6
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	Ethyl 1,2-dihydro-4-hydroxy-2-oxo-1,6-naphthyridine-3-carboxylate; 4-Hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine-3-carboxylic Acid Ethyl Ester; 1,6-Naphthyridine-3-carboxylic acid, 1,2-dihydro-4-hydroxy-2-oxo-, ethyl ester; Ethyl 4-hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine-3-carboxylate; 3-Carbethoxy-4-hydroxy-1,6-naphthyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridine-3-Carboxylic Acid, 1,2-Dihydro-4-Hydroxy-2-Oxo-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.