Description

(1E)-1-tert-Butoxy-1-(Trimethylsilyloxy)Propene is a high-value organosilicon reagent featuring a unique combination of tert-butoxy and trimethylsilyloxy protecting groups on a propenyl backbone. This compound matters as a versatile synthetic building block, enabling controlled reactions in complex organic synthesis where precise functional group manipulation is critical. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules, particularly for introducing protected carbonyl equivalents.
• Advanced Organic Synthesis: Used in aldol-type reactions, nucleophilic additions, and as a precursor to enolates under mild conditions.
• Polymer Chemistry: Serves as a functional monomer or chain-transfer agent in the development of specialty silicones and tailored polymeric materials.
• Agrochemical Research: Employed in the synthesis of novel active ingredients and fine chemicals for crop protection.
• Material Science: Utilized in surface modification and the creation of silicon-containing hybrid organic-inorganic materials.

Basic Information

Product Name	(1E)-1-tert-Butoxy-1-(Trimethylsilyloxy)Propene
CAS No.	72658-10-7
Molecular Formula	C10H22O2Si
Molecular Weight	202.37 g/mol
Synonyms	1-(tert-Butoxy)-1-[(trimethylsilyl)oxy]-1-propene; (E)-1-tert-Butoxy-1-(trimethylsilyloxy)prop-1-ene; 1-tert-Butoxy-1-(trimethylsilyloxy)propene; tert-Butoxy(trimethylsilyloxy)propene; TBSO-protected tert-butyl enol ether; (E)-1-(tert-Butoxy)-1-(trimethylsiloxy)propene; 72658-10-7
EINECS	Contact for details

Quality Control

Our (1E)-1-tert-Butoxy-1-(Trimethylsilyloxy)Propene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.