Description

6-(2,2,2-Trifluoroethoxy)Pyridin-3-Amine is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique trifluoroethoxy substituent imparts distinct electronic and steric properties, making it a valuable intermediate for creating novel compounds with enhanced biological activity and material characteristics. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the research of central nervous system (CNS) agents, kinase inhibitors, and anti-infective drugs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine moiety can improve metabolic stability and membrane permeability.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to modify solubility and thermal properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated heterocyclic structures.

Basic Information

Product Name	6-(2,2,2-Trifluoroethoxy)Pyridin-3-Amine
CAS No.	72617-82-4
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	3-Amino-6-(2,2,2-trifluoroethoxy)pyridine; 6-(2,2,2-Trifluoroethoxy)-3-pyridinamine; 5-Amino-2-(2,2,2-trifluoroethoxy)pyridine; 2-(Trifluoroethoxy)-5-aminopyridine; 3-Pyridinamine, 6-(2,2,2-trifluoroethoxy)-; 6-(Trifluoroethoxy)pyridin-3-amine; 5-Amino-2-(trifluoroethoxy)pyridine
EINECS	Contact for details

Quality Control

Our 6-(2,2,2-Trifluoroethoxy)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-grade material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.