Description

2-Amino-3-Chloro-5-(Trifluoromethyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and chloro substitution pattern makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at the pharmaceutical and agrochemical industries for the research and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysis and specialty polymers.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Liquid Crystal & Electronic Chemical Intermediate: Potential use in the synthesis of fluorinated compounds for electronic materials.

Basic Information

Product Name	2-Amino-3-Chloro-5-(Trifluoromethyl)Pyridine
CAS No.	72600-65-8
Molecular Formula	C6H4ClF3N2
Molecular Weight	196.56 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)pyridin-2-amine; 2-Amino-3-chloro-5-trifluoromethylpyridine; 2-Pyridinamine, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-trifluoromethyl-2-pyridylamine; 2-Amino-3-chloro-α,α,α-trifluoro-p-toluidine (related); 5-(Trifluoromethyl)-3-chloropyridin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.