Description

Diethyl (3,4-Dimethylphenyl)Phosphonate is a high-purity organophosphorus compound, serving as a critical intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with phosphonate or phosphonic acid moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the phosphonate group is integral to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphine-based ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of flame retardants, plasticizers, and other functional additives for polymers.
• Organic Synthesis Building Block: Utilized in Horner-Wadsworth-Emmons (HWE) olefination reactions to generate alkenes with high stereoselectivity.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on novel organophosphorus chemistry.

Basic Information

Product Name	Diethyl (3,4-Dimethylphenyl)Phosphonate
CAS No.	72596-30-6
Molecular Formula	C₁₂H₁₉O₃P
Molecular Weight	242.25 g/mol
Synonyms	Diethyl (3,4-Dimethylphenyl)Phosphonate; Diethyl 3,4-Dimethylphenylphosphonate; (3,4-Dimethylphenyl)phosphonic Acid Diethyl Ester; Diethyl 3,4-Xylylphosphonate; Phosphonic Acid, P-(3,4-Dimethylphenyl)-, Diethyl Ester; Diethyl P-(3,4-Dimethylphenyl)phosphonate; 72596-30-6; 3,4-Dimethylphenylphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl (3,4-Dimethylphenyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.