Description

Benzyl tert-Butyl Malonate is a high-purity, versatile chemical intermediate essential for advanced organic synthesis. Its unique structure, featuring both benzyl and tert-butyl protecting groups, makes it a critical building block for constructing complex molecules with high selectivity and yield. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing malonate-derived moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and performance chemicals requiring specific ester functionalities.
• Peptidomimetics Research: Employed in medicinal chemistry for the design and synthesis of peptide analogs and enzyme inhibitors.
• Polymer Modification: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Asymmetric Synthesis: Utilized in chiral synthesis protocols due to the differential reactivity of its ester groups.

Basic Information

Product Name	Benzyl tert-Butyl Malonate
CAS No.	72594-86-6
Molecular Formula	C₁₄H₁₈O₄
Molecular Weight	250.29 g/mol
Synonyms	Benzyl tert-butyl propanedioate; Propanedioic acid, (phenylmethyl)-, 1,3-bis(1,1-dimethylethyl) ester; tert-Butyl benzyl malonate; Dibenzyl tert-butyl malonate (common misnomer); Benzyl 1-(tert-butoxy)-1,3-dioxopropane-2-carboxylate; Malonic acid, benzyl-, bis(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Every batch of Benzyl tert-Butyl Malonate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation by IR and NMR, and impurity profile, is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.