Description

2-Chloro-3-Nitro-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and nitrated pyridine core. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its trifluoromethyl group imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development teams in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, insecticides, and fungicides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas targeting central nervous system (CNS) disorders and anti-infective agents.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in catalytic processes and coordination chemistry.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up campaigns.

Basic Information

Item	Details
Product Name	2-Chloro-3-Nitro-5-(Trifluoromethyl)Pyridine
CAS No.	72587-15-6
Molecular Formula	C6H2ClF3N2O2
Molecular Weight	226.54 g/mol
Synonyms	2-Chloro-3-nitro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-chloro-3-nitropyridine; 3-Nitro-2-chloro-5-trifluoromethylpyridine; 2-Chloro-3-nitro-5-trifluoromethylpyridine; Pyridine, 2-chloro-3-nitro-5-(trifluoromethyl)-; 72587-15-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.