Description

3-(2-Chloroactyl)-2-[(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine-2-Oxide is a specialized organophosphorus compound of significant interest in advanced chemical synthesis. This molecule serves as a critical intermediate for the development of novel pharmaceutical agents and biologically active compounds. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug development.
• Chemical Research: Used in academic and industrial research for studying organophosphorus chemistry and developing new synthetic methodologies.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and plant growth regulators.
• Ligand Synthesis: Utilized for creating specialized ligands and chelating agents in coordination chemistry and catalysis.
• Bioconjugation Chemistry: Potential use in the development of linker molecules for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science: Intermediate for synthesizing functional polymers and advanced materials with specific chemical properties.

Basic Information

Product Name	3-(2-Chloroactyl)-2-[(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine-2-Oxide
CAS No.	72578-71-3
Molecular Formula	C7H14Cl2N2O3P
Molecular Weight	285.08 g/mol
Synonyms	2-[(2-Chloroethyl)amino]-3-(2-chloroacetyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; 3-(2-Chloroacetyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; Cyclophosphamide Impurity; Cyclophosphamide Related Compound; Oxazaphosphorine derivative; N-(2-Chloroethyl)-N'-(2-chloroacetyl)phosphorodiamidic acid cyclic propylene ester; Phosphorodiamidic acid, N-(2-chloroethyl)-N'-(2-chloroacetyl)-, cyclic propylene ester
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chloroactyl)-2-[(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine-2-Oxide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters are provided with each shipment. We support compliance with cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.