Description

(1R,5R,6S)-Rel-2-Thiabicyclo[3.1.0]Hex-3-Ene-6-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic structure. This compound is of significant value in organic synthesis, particularly for constructing complex molecular architectures with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug molecules and potential APIs.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce the bicyclo[3.1.0]hexane scaffold into target compounds.
• Medicinal Chemistry Research: Serves as a versatile precursor in drug discovery programs for exploring new chemical entities.
• Ligand and Catalyst Development: Can be used to develop novel chiral ligands or organocatalysts due to its rigid, three-dimensional structure.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty and performance chemicals requiring specific stereochemistry.

Basic Information

Product Name	(1R,5R,6S)-Rel-2-Thiabicyclo[3.1.0]Hex-3-Ene-6-Carboxylic Acid Ethyl Ester
CAS No.	72554-41-7
Molecular Formula	C9H12O2S
Molecular Weight	184.26 g/mol
Synonyms	Ethyl (1R,5R,6S)-rel-2-thiabicyclo[3.1.0]hex-3-ene-6-carboxylate; rel-(1R,5R,6S)-2-Thiabicyclo[3.1.0]hex-3-ene-6-carboxylic acid ethyl ester; Bicyclo[3.1.0]hex-3-ene-6-carboxylic acid, 2-thia-, ethyl ester, (1R,5R,6S)-rel-; Ethyl 2-thiabicyclo[3.1.0]hex-3-ene-6-carboxylate; 72554-41-7
EINECS	Contact for details

Quality Control

Our (1R,5R,6S)-Rel-2-Thiabicyclo[3.1.0]Hex-3-Ene-6-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.