Description

3-Isocyanopropyl Toluene-p-Sulphonate is a specialized organic sulfonate ester derivative, widely recognized as a versatile and reactive chemical intermediate. Its core value lies in its ability to act as a protected isocyanate precursor, facilitating controlled chemical synthesis in advanced manufacturing processes. This compound is essential for researchers and industrial chemists in the pharmaceutical, agrochemical, and polymer sectors, where it is used to introduce functional groups and build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring controlled isocyanate release.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive nature enables the creation of novel active molecules.
• Polymer Modification: Serves as a cross-linking agent or functional monomer in the development of specialty polymers, polyurethanes, and coatings with tailored properties.
• Peptide Chemistry: Employed as a coupling reagent or protecting group strategy in solid-phase peptide synthesis (SPPS) and related bioconjugation techniques.
• Material Science Research: A valuable reagent for developing novel organic materials, dendrimers, and functional surfaces in academic and industrial R&D laboratories.
• Chemical Derivatization: Used to modify other organic compounds, introducing sulfonate ester groups for improved solubility, reactivity, or analytical detection.

Basic Information

Product Name	3-Isocyanopropyl Toluene-p-Sulphonate
CAS No.	72548-55-1
Molecular Formula	C11H13NO4S
Molecular Weight	255.29 g/mol
Synonyms	p-Toluenesulfonic Acid 3-Isocyanopropyl Ester; 3-Isocyanopropyl Tosylate; 3-Isocyanopropyl 4-Methylbenzenesulfonate; Tosyloxypropyl Isocyanate; 1-Isocyanato-3-[(4-methylphenyl)sulfonyl]oxypropane; 3-Tosyloxypropyl Isocyanate; (3-Isocyanatopropoxy)(4-methylphenyl)sulfane
EINECS	Contact for details

Quality Control

Our 3-Isocyanopropyl Toluene-p-Sulphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.