Description

(5S,3R)-5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-Octahydro-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is a complex, high-purity spirocyclic organic compound featuring a fused naphthofuran-dione structure. This compound serves as a critical chiral intermediate or building block in advanced organic synthesis, particularly for pharmaceuticals and specialty chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require sophisticated molecular scaffolds for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex spirocyclic structure for unique biological activity.
• Asymmetric Synthesis: Serves as a sophisticated substrate or ligand precursor in catalytic asymmetric reactions due to its defined stereochemistry.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, dyes, and advanced materials requiring specific three-dimensional architecture.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry, total synthesis projects, and exploring new reaction pathways.

Basic Information

Product Name	(5S,3R)-5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-Octahydro-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione
CAS No.	72541-00-5
Molecular Formula	C20H20O5
Molecular Weight	340.37 g/mol
Synonyms	7'α-Methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione, 5-(3-furanyl)-3',4,5,5',5'aβ,7',8',8'aα-octahydro-, (5S,3'R)-; Spiro[naphtho[1,8-bc]furan-6(6H),3'-[2H]furan]-2,2'(4'H)-dione derivative; (3'R,5S,5'aβ,7'α,8'aα)-5-(3-Furanyl)octahydro-7'-methyl-; Complex Furan-Spiro-Dione; Chiral Naphthofuran Dione Intermediate.
EINECS	Contact for details

Quality Control

Our (5S,3R)-5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-Octahydro-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, MS) are provided to guarantee batch-to-batch consistency and support your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.