Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group, makes it an indispensable intermediate for creating molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysis and in the creation of specialty polymers and electronic materials.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Pyridine
CAS No.	72537-17-8
Molecular Formula	C6H2ClF4N
Molecular Weight	199.53 g/mol
Synonyms	2-Fluoro-3-chloro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-chloro-2-fluoropyridine; 3-Chloro-2-fluoro-5-trifluoromethylpyridine; Pyridine, 3-chloro-2-fluoro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical property, ensure it is stored separately from bases and moisture-sensitive compounds.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.