Description

Streptozocin CAS NO 72521-89-2 is a potent nitrosourea antibiotic and alkylating agent derived from *Streptomyces achromogenes*. This compound is of critical importance in biomedical research, particularly for its selective toxicity towards pancreatic beta cells. It is primarily utilized by pharmaceutical researchers and life science laboratories for the induction of experimental diabetes in animal models and in studies investigating cancer therapeutics.

Application

• Induction of Experimental Diabetes: Widely used in preclinical research to create chemically-induced (Type 1) diabetes models in rodents for studying disease mechanisms and potential treatments.
• Oncology Research: Employed as a chemotherapeutic agent in studies due to its DNA alkylating properties, with historical use against pancreatic islet cell carcinoma and other malignancies.
• β-Cell Biology Studies: Serves as a selective toxin to investigate the function, regeneration, and pathology of pancreatic insulin-producing cells.
• Pharmacology & Toxicology: Used to assess drug metabolism and organ-specific toxicity in diabetic versus non-diabetic animal models.
• Biochemical Research: Applied in studies of DNA damage and repair mechanisms, as well as cellular responses to alkylating agents.

Basic Information

Product Name	Streptozocin
CAS No.	72521-89-2
Molecular Formula	C8H15N3O7
Molecular Weight	265.22 g/mol
Synonyms	Streptozotocin; Zanosar; STZ; Streptozocin; NSC-85998; U-9889; 2-Deoxy-2-({[methyl(nitroso)amino]carbonyl}amino)-α-D-glucopyranose; N-(Methylnitrosocarbamoyl)-α-D-glucosamine
EINECS	Contact for details

Quality Control

Our Streptozocin is manufactured and tested to meet high-purity standards suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to pale yellow powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Biological Activity	Confirmed by in-vitro assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.