Description

2-Phenylpiperidine-2-Carboxylic Acid is a specialized chiral piperidine derivative, a high-value building block in advanced organic synthesis. Its core value lies in its rigid, functionalized structure, which serves as a privileged scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: A valuable reference standard and starting material in academic and industrial research exploring piperidine chemistry and structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Phenylpiperidine-2-Carboxylic Acid
CAS No.	72518-42-4
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	2-Phenyl-2-piperidinecarboxylic acid; 2-Phenylpiperidine-2-carboxylic acid; 2-Carboxy-2-phenylpiperidine; α-Phenylpipecolic acid; (RS)-2-Phenylpiperidine-2-carboxylic acid; DL-2-Phenylpiperidine-2-carboxylic acid; 2-Phenyl-2-piperidinecarboxylic acid; 2-Phenyl-2-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Phenylpiperidine-2-Carboxylic Acid is produced and tested under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up applications. Our products undergo rigorous quality testing, including chiral purity analysis, to meet the exacting standards of the pharmaceutical and fine chemical industries. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.