Description

6-Chloro-trans-2-Hexenoic Acid Ethyl Ester is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in the reactive chloro and ester functionalities attached to an unsaturated carbon chain, making it a key precursor for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of prostaglandins, other bioactive molecules, and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where specific stereochemistry is required.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing specific unsaturated esters and lactones that contribute to complex aroma profiles.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its reactive sites.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, Michael additions, and other C-C bond-forming transformations in research and process chemistry.

Basic Information

Product Name	6-Chloro-trans-2-Hexenoic Acid Ethyl Ester
CAS No.	72448-92-1
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	Ethyl (E)-6-Chloro-2-hexenoate; (E)-Ethyl 6-Chlorohex-2-enoate; trans-6-Chloro-2-hexenoic Acid Ethyl Ester; Ethyl trans-6-Chloro-2-hexenoate; 6-Chloro-(E)-2-hexenoic Acid Ethyl Ester; 2-Hexenoic acid, 6-chloro-, ethyl ester, (2E)-; Ethyl (2E)-6-chloro-2-hexenoate
EINECS	Contact for details

Quality Control

Our 6-Chloro-trans-2-Hexenoic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), isomeric purity, and impurity profiles. Our quality commitment supports applications requiring reliable and reproducible synthetic intermediates for GMP and non-GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isomeric Purity (trans)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.