Description

Benzeneacetamide, 3-Methoxy-n-(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy] - CAS NO 72361-06-9 is a specialized organosilicon derivative of a substituted benzeneacetamide, designed for advanced synthetic applications. This compound is valued for its dual trimethylsilyl (TMS) protecting groups, which offer enhanced stability and reactivity control in sensitive chemical transformations. It serves as a critical synthetic intermediate for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of complex organic molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Advanced Organic Synthesis: Used as a protected synthon in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions.
• Fine Chemical Production: Intermediate for creating specialty chemicals, including dyes, pigments, and advanced materials.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, or plant growth regulators.
• Material Science: Potential monomer or modifier in the synthesis of silicon-containing polymers and advanced resins.
• Academic & R&D: A valuable reagent for methodological development in university and corporate research laboratories focusing on organosilicon chemistry.

Basic Information

Product Name	Benzeneacetamide, 3-Methoxy-n-(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy]
CAS No.	72361-06-9
Molecular Formula	C15H27NO3Si2
Molecular Weight	325.56 g/mol
Synonyms	3-Methoxy-N-(trimethylsilyl)-4-[(trimethylsilyl)oxy]benzeneacetamide; 4-(Trimethylsiloxy)-3-methoxy-N-(trimethylsilyl)phenylacetamide; N-(Trimethylsilyl)-2-(4-(trimethylsiloxy)-3-methoxyphenyl)acetamide; 2-(4-(Trimethylsilyloxy)-3-methoxyphenyl)-N-(trimethylsilyl)acetamide; TMS-protected 3-methoxy-4-hydroxybenzeneacetamide; Bis-TMS Vanillin Acetamide Derivative
EINECS	Contact for details

Quality Control

Our Benzeneacetamide, 3-Methoxy-n-(Trimethylsilyl)-4-[(Trimethylsilyl)Oxy] is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.