Description

L-Lysine, N2,N6-Bis(Trimethylsilyl)-5-[(Trimethylsilyl)Oxy]-, Trimethylsilyl Ester is a fully silylated derivative of the essential amino acid L-Lysine, designed to enhance volatility and stability for advanced analytical and synthetic procedures. This compound is critical for researchers and manufacturers requiring precise derivatization to facilitate gas chromatography (GC) and mass spectrometry (MS) analysis of amino acids. It serves as a key protected intermediate and analytical standard in pharmaceutical research, proteomics, and the synthesis of complex peptides and bio-conjugates.

Application

• Derivatization Agent for GC/MS Analysis: Used to convert amino acids into volatile, thermally stable trimethylsilyl (TMS) derivatives for accurate identification and quantification in complex biological matrices.
• Pharmaceutical Intermediate: Serves as a protected building block in the multi-step synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Proteomics and Metabolomics Research: Essential for sample preparation in high-throughput profiling of amino acids and metabolic pathways.
• Reference Standard: Provides a high-purity benchmark for method development, validation, and quality control in analytical laboratories.
• Biochemical Research: Employed in studies investigating lysine metabolism, post-translational modifications, and enzyme mechanisms.
• Nutritional Analysis: Used in the derivatization and analysis of lysine content in food, feed, and nutritional supplements.

Basic Information

Product Name	L-Lysine, N2,N6-Bis(Trimethylsilyl)-5-[(Trimethylsilyl)Oxy]-, Trimethylsilyl Ester
CAS No.	72361-02-5
Molecular Formula	C21H51NO3Si4
Molecular Weight	506.0 g/mol
Synonyms	L-Lysine, N2,N6-bis(trimethylsilyl)-5-[(trimethylsilyl)oxy]-, trimethylsilyl ester; N2,N6,O5-Tris(trimethylsilyl)-L-lysine trimethylsilyl ester; Tris(trimethylsilyl)-L-lysine TMS ester; L-Lysine TMS derivative; Fully silylated L-lysine; Nα,Nε,O-Tris(trimethylsilyl)-L-lysine trimethylsilyl ester; Lysine TMS; Amino acid derivatization reagent 72361-02-5
EINECS	Contact for details

Quality Control

Our L-Lysine, N2,N6-Bis(Trimethylsilyl)-5-[(Trimethylsilyl)Oxy]-, Trimethylsilyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee the material meets the stringent requirements for research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.