Description

(5-Iodo-Pyridin-3-Yl)-Methanol is a versatile iodinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the reactive iodomethyl group, which enables efficient functionalization and cross-coupling reactions for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Used to create specialized pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for bio-conjugation and imaging studies.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	(5-Iodo-Pyridin-3-Yl)-Methanol
CAS No.	72299-58-2
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	5-Iodonicotinyl alcohol; 3-(Hydroxymethyl)-5-iodopyridine; (5-Iodo-3-pyridyl)methanol; 5-Iodo-3-pyridinemethanol; 5-Iodo-3-hydroxymethylpyridine; 5-Iodopyridin-3-ylmethanol; 3-Pyridinemethanol, 5-iodo-
EINECS	Contact for details

Quality Control

Our (5-Iodo-Pyridin-3-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.