Description

3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-1-(Phenylmethyl)-, Diethyl Ester is a specialized dihydropyridine derivative, a class of compounds renowned for their significant biological and chemical activity. This compound matters as a key advanced intermediate in the synthesis of complex molecules, offering a versatile scaffold for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the development of new active ingredients, particularly those targeting cardiovascular and neurological pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel calcium channel blockers and other dihydropyridine-based active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex nitrogen-containing heterocycles in medicinal chemistry.
• Biochemical Research: Employed as a tool compound in pharmacological studies to investigate ion channel modulation and related cellular mechanisms.
• Material Science: Potential use as an intermediate for specialty chemicals and functional materials requiring specific aromatic and heterocyclic architectures.

Basic Information

Product Name	3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-1-(Phenylmethyl)-, Diethyl Ester
CAS No.	72284-55-0
Molecular Formula	C25H26N2O6
Molecular Weight	450.49 g/mol
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(phenylmethyl)-3,5-pyridinedicarboxylic acid diethyl ester; Diethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(phenylmethyl)-3,5-pyridinedicarboxylate; 1-Benzyl-4-(3-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(phenylmethyl)-, diethyl ester; 1-Benzyl-4-(3-nitrophenyl)-1,4-dihydropyridine derivative; DHP derivative CAS 72284-55-0
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), ensuring consistency for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports the stringent requirements of pharmaceutical R&D and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.