Description

8-(1,1-Dimethylethyl)-1-Oxaspiro[4.5]Decan-2-One is a high-purity, specialized organic compound with the CAS number 72258-83-4. This spirocyclic lactone derivative serves as a critical advanced intermediate and key building block in the synthesis of complex molecules. It is primarily required by R&D and production teams in the pharmaceutical and fine chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those requiring complex spirocyclic or bridged-ring architectures.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its unique structure contributes to specific biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing novel musk compounds and other specialty aroma chemicals.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex natural product analogs and other sophisticated organic molecules.
• Ligand & Catalyst Development: Acts as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	8-(1,1-Dimethylethyl)-1-Oxaspiro[4.5]Decan-2-One
CAS No.	72258-83-4
Molecular Formula	C13H22O2
Molecular Weight	210.31 g/mol
Synonyms	8-tert-Butyl-1-oxaspiro[4.5]decan-2-one; 1-Oxaspiro[4.5]decan-2-one, 8-(1,1-dimethylethyl)-; 8-(tert-Butyl)-1-oxaspiro[4.5]decan-2-one; tert-Butyl spirocyclic lactone; Spiro[4.5]decan-2-one, 8-tert-butyl-1-oxa-; 72258-83-4; 8-tert-Butyl-1-oxa-spiro[4.5]decan-2-one
EINECS	Contact for details

Quality Control

Our 8-(1,1-Dimethylethyl)-1-Oxaspiro[4.5]Decan-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.