Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (1R,2R,4R)- (9Ci) is a high-purity, chiral bicyclic compound that serves as a critical synthetic intermediate. Its defined stereochemistry and rigid norbornene-based structure make it an invaluable building block for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require enantiomerically pure intermediates for applications in asymmetric synthesis and polymer science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of prostaglandins, antiviral agents, and other bioactive molecules requiring specific stereochemistry.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of specialized ligands for transition metal catalysts that drive enantioselective reactions, such as hydrogenations and cycloadditions.
• Advanced Polymer Monomer: Serves as a functional monomer for creating specialty polymers with unique thermal and mechanical properties, including polymers of intrinsic microporosity (PIMs) and shape-persistent materials.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to introduce the norbornene scaffold into target molecules for agrochemical and material science research.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrances, flavors, and other high-value fine chemicals where stereochemical purity is paramount.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (1R,2R,4R)- (9Ci)
CAS No.	72203-34-0
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester; (-)-exo-5-Norbornene-2-carboxylic acid methyl ester; (1R,2R,4R)-(-)-Methyl 5-norbornene-2-carboxylate; endo-(1R)-Norborn-5-ene-2-carboxylic acid methyl ester; Methyl (1R,2R,4R)-bicyclo[2.2.1]hept-5-ene-2-carboxylate; (1R,2R,4R)-Methyl 5-norbornene-2-carboxylate; exo-(-)-Methyl 5-norbornene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (1R,2R,4R)- (9Ci) is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to guarantee enantiomeric excess (ee) and chemical purity meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.