Description

5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Acetic Acid Methyl Ester is a protected derivative of indole-3-acetic acid, a key plant hormone and versatile synthetic intermediate. This compound is valued for its role in organic synthesis, where the trimethylsilyl (TMS) protecting group enhances stability and alters reactivity for selective chemical transformations. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex indole-based drug candidates, including potential CNS-active compounds and anti-inflammatory agents.
• Agrochemical Research: Used in the development and study of synthetic auxins and other plant growth regulators for crop protection and enhancement.
• Organic Synthesis: Acts as a protected precursor for indole-3-acetic acid, facilitating multi-step synthesis where selective deprotection is required.
• Biochemical Research: Employed in studies investigating plant hormone signaling pathways and the physiological effects of auxin analogs.
• Material Science: Potential intermediate for the synthesis of specialized organic compounds used in advanced material applications.

Basic Information

Product Name	5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Acetic Acid Methyl Ester
CAS No.	72101-35-0
Molecular Formula	C₁₄H₁₉NO₃Si
Molecular Weight	277.40 g/mol
Synonyms	Methyl 5-(trimethylsilyloxy)-1H-indole-3-acetate; 5-(Trimethylsiloxy)indole-3-acetic Acid Methyl Ester; 3-Indoleacetic Acid, 5-(Trimethylsilyloxy)-, Methyl Ester; 5-Hydroxyindole-3-acetic Acid Methyl Ester Trimethylsilyl Ether; 5-TMS-Oxy-IAA-ME; 5-O-TMS-IAA-Methyl Ester
EINECS	Contact for details

Quality Control

Our 5-[(Trimethylsilyl)Oxy]-1H-Indole-3-Acetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.