Description

5-Chloro-2-Picoline is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a chlorine atom adjacent to the nitrogen in the pyridine ring, makes it a valuable precursor for pharmaceuticals, agrochemicals, and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active compounds and ligands.

Application

• Pharmaceutical Intermediate: Key synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of receptor antagonists and enzyme inhibitors.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the chloropyridine moiety enhances biological activity.
• Ligand & Catalyst Preparation: Serves as a precursor for nitrogen-donor ligands in transition metal catalysis, useful in cross-coupling and other fine chemical reactions.
• Material Science: Building block for the synthesis of functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new heterocyclic chemistry and structure-activity relationships.

Basic Information

Product Name	5-Chloro-2-Picoline
CAS No.	72093-07-3
Molecular Formula	C6H6ClN
Molecular Weight	127.57 g/mol
Synonyms	2-Methyl-5-chloropyridine; 5-Chloro-2-methylpyridine; 5-Chloro-2-picoline; 2-Picoline, 5-chloro-; 5-Chloro-2-methylpyridine; 5-Chloro-2-picoline; 5-Chloro-2-methylpyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Picoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.