Description

(Z)-2-Methyl-2-Butenoic Acid [(3As,4R,5R,6E,8R,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-5,8-Dihydroxy-6,10-Dimethyl-3-Methylene-2-Oxocyclodeca[B]Furan-4-Yl] Ester is a complex, high-purity chemical ester with a defined stereochemistry, making it a valuable chiral building block for advanced organic synthesis. Its intricate fused-ring structure is of significant interest for the research and development of novel bioactive compounds. This product is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex macrolide or polyketide-derived structures.
• Advanced Organic Synthesis: Used as a specialized building block for constructing complex natural product analogs and molecules with specific stereochemical configurations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new therapeutic avenues, leveraging its unique fused furan and cyclodecane framework.
• Biochemical Research: Potential use as a probe or precursor in studying biological pathways and enzyme interactions due to its stereochemically defined hydroxyl groups.
• Fine Chemical Production: Applicable in the multi-step synthesis of high-value specialty chemicals where control over stereochemistry is paramount.

Basic Information

Product Name	(Z)-2-Methyl-2-Butenoic Acid [(3As,4R,5R,6E,8R,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-5,8-Dihydroxy-6,10-Dimethyl-3-Methylene-2-Oxocyclodeca[B]Furan-4-Yl] Ester
CAS No.	72065-36-2
Molecular Formula	C20H28O6
Molecular Weight	364.44 g/mol
Synonyms	2-Methyl-2-butenoic acid (3aR,4R,5R,6E,8R,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-5,8-dihydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester; (Z)-Tiglic Acid Ester of a Dihydroxy-Dimethyl-Methylene-Oxocyclodecafuranyl Alcohol; Stereo-defined Macrolide Ester; Cyclodeca[B]Furan-4-Yl Tiglate Derivative; CAS 72065-36-2
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity essential for research applications. Identity and purity are confirmed via advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each batch to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.