Description

(7S,7Aβ,14Aα)-Dodecahydro-8α,9β-Dihydroxy-7α,14α-Methano-4H,6H-Dipyrido[1,2-A:1',2'-E][1,5]Diazocin-4-One is a complex, high-purity alkaloid derivative with a rigid polycyclic structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique stereochemistry and functional groups make it an invaluable building block for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and analgesic targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Development: Acts as a precursor in the research phase for creating novel active ingredients with specific modes of action.
• Academic & Institutional Research: Serves as a reference standard or starting material for studies in organic synthesis methodology and alkaloid chemistry.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing production processes for target molecules in pilot plants.

Basic Information

Product Name	(7S,7Aβ,14Aα)-Dodecahydro-8α,9β-Dihydroxy-7α,14α-Methano-4H,6H-Dipyrido[1,2-A:1',2'-E][1,5]Diazocin-4-One
CAS No.	72047-67-7
Molecular Formula	C₁₅H₂₂N₂O₃
Molecular Weight	278.35 g/mol
Synonyms	8α,9β-Dihydroxy-7α,14α-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one, dodecahydro-, (7S,7aβ,14aα)-; 7α,14α-Methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one, dodecahydro-8α,9β-dihydroxy-, (7S,7aβ,14aα)-; Dihydroxymethanodipyridodiazocinone; Advanced Oripavine Derivative Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (7S,7Aβ,14Aα)-Dodecahydro-8α,9β-Dihydroxy-7α,14α-Methano-4H,6H-Dipyrido[1,2-A:1',2'-E][1,5]Diazocin-4-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, chiral purity, and impurity profiles. Our quality protocols are designed to meet the exacting standards of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.