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1-[2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranosyl]Piperidine CAS NO 72021-24-0


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CAS No.:72021-24-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-[2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranosyl]Piperidine is a sophisticated, fully protected glycosyl donor derivative, crucial for advanced synthetic organic chemistry. This compound is engineered to provide exceptional stability and reactivity control in complex glycosylation reactions, a cornerstone of modern pharmaceutical and carbohydrate research. It is an essential intermediate for researchers and process chemists in the development of novel therapeutics, complex oligosaccharides, and high-value specialty chemicals.

Application

  • Glycosylation Reagent: A key protected donor for the stereoselective synthesis of complex glycosidic linkages in oligosaccharides and glycoconjugates.
  • Pharmaceutical Intermediate: Critical for the research and development of glycosidase inhibitors, antiviral agents, and carbohydrate-based drugs.
  • Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation mechanisms and developing new synthetic methodologies.
  • Glycobiology Tool: Enables the construction of defined glycan structures for biological activity studies and diagnostic applications.
  • Specialty Chemical Synthesis: Serves as a building block for surfactants, chiral ligands, and other high-value functional materials derived from carbohydrates.

Basic Information

Product Name 1-[2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranosyl]Piperidine
CAS No. 72021-24-0
Molecular Formula C24H53NO5Si4
Molecular Weight 566.06 g/mol
Synonyms 1-(2,3,4,6-Tetra-O-trimethylsilyl-β-D-glucopyranosyl)piperidine; Tetra-O-trimethylsilyl-β-D-glucopyranosyl piperidine; β-D-Glucopyranoside, 2,3,4,6-tetrakis-O-(trimethylsilyl)-, 1-(1-piperidinyl)-; Piperidine, 1-(2,3,4,6-tetra-O-trimethylsilyl-β-D-glucopyranosyl)-; TMS-protected glucosyl piperidine; Per-TMS glucosyl piperidine derivative
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Quality Control

Every batch of 1-[2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranosyl]Piperidine is synthesized and purified under controlled conditions to ensure the highest standards of chemical integrity and lot-to-lot consistency. Our products undergo rigorous quality testing, including HPLC for purity and NMR for structural confirmation, to meet the exacting requirements of research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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